The ethical infrastructure of legal practice in larger law firms: values, policy and behaviour

The article examines the impact of the cultures and organisational structures of large law firms on individual lawyers' ethics. The paper suggests that large law firms in Australia should consciously design and implement 'ethical infrastructures' to both counteract pressures for misbehaviour and positively promote ethical behaviour and discussion. The paper goes on to explain what implementing ethical infrastructures in law firms could and should mean by reference to what Australian law firms are already doing and US innovations in this area. Finally, the paper warns that the 'ethical infrastructure' of a firm should not be seen merely as the formal ethics policies explicitly enunciated by management. Formal and legalistic ethical infrastructures that fail to support or encourage the development of individual lawyers' awareness oftheir own ethical values and ethical judgment in practice will be useless

Subjective Well-being of Primary Health Care Patients in the Western Cape, South Africa

Background: Patients living with a chronic illness face many challenges in their lives such as an altered body image, physical pain or discomfort, the need for frequent medical visits and the negative side effects of treatment. To this extent their sense of personal or subjective well-being may be compromised by the severity and chronicity of their illness. The aim of the present study was to explore the level of subjective well-being and its relationship with coping, quality of life and support from family and friends among a sample of Black South Africans attending semi-rural public clinics for treatment for hypertension and diabetes. This study was part of a larger project on treatment adherence to medication among patients living with these conditions. Methods: A convenience sample of 117 patients aged between 22 and 82 years (M=52.36, SD=13.24), receiving treatment for hypertension (n=79) or diabetes (n=24) at three primary health care clinics in the Boland area of the Western Cape were asked to participate in this study. Of the total sample, 14 (12%) were diagnosed with both conditions. Participants were asked to complete a questionnaire battery consisting of the Satisfaction with Life Scale, the Coping Strategy Indicator, the Functioning Assessment of Non-Life Threatening Conditions and the Perceived Social Support Scale. Results: The mean score of the Satisfaction with Life Scale was 28.70, which was significantly higher than those of other studies using this mea-sure. In order to address the problem of experiment-wise error, commonly associated with the use of multiple statistical comparisons, we used the Bonferronni correction in arriving at probability levels in determining statistical significance. On average the sample as a whole appeared to be largely satisfied. The mean scores on the two of the subscales of the Coping Strategy Indicator were significantly different from those obtained from other South African samples. On the Functioning Assessment of Non-Life Threatening Conditions, the mean scores on the subscales but not the total score was significantly higher than other South African samples. Conclusions: In general, participants scored significantly higher on all of the measuring instruments compared with other South African samples, indicating high levels of life satisfaction, coping, and support from others. We found no relationship between life satisfaction and gender. Age however correlated positively with satisfaction with Life, Support from family, social and emotional well being and Quality of Life, which concurs with the findings of previous studies. Contrary to other studies we found a significant negative correlation between education and SWLS but no relationship between employment and SWLS. Our sample also reported higher levels of support from friends and family that were significantly higher than those of other South African samples. The mean scores on all the subscales of the Coping Strategy Indicator were higher than that of other South African samples. South African Family Practice Vol. 50 (3) 2008: pp. 68-68

Testing climate-smart agricultural technologies and practices in Southeast Asia: a manual for priority setting

The project Integrated agricultural technologies for enhanced adaptive capacity and resilient livelihoods in climate-smart villages (CSVs) of Southeast Asia aims to provide climate-smart agriculture options to enhance adaptive capacity among CSV farmers and stakeholders, and contribute to more climate-resilient livelihoods, in selected sites in Cambodia, Lao PDR and Vietnam. In order to facilitate a participatory process leading to the selection of the most effective technologies and practices, a team of CCAFS researchers worked on the development of a prioritysetting manual. This manual includes a number of principles and a sequence of six steps which were developed based on a critical review of past and ongoing participatory climate-smart technology selection experiences carried out as part of CCAFS in Africa and Asia, the experiences of the research team with similar processes and activities and were complemented by insights from the literature. A draft of the manual was put to test by the CIAT-Asia coordinated project research team in Ma village in the north of Vietnam in July 2015

Human Stem Cells for Ophthalmology: Recent Advances in Diagnostic Image Analysis and Computational Modelling

\ua9 2023, The Author(s).Purpose of Review: To explore the advances and future research directions in image analysis and computational modelling of human stem cells (hSCs) for ophthalmological applications. Recent Findings: hSCs hold great potential in ocular regenerative medicine due to their application in cell-based therapies and in disease modelling and drug discovery using state-of-the-art 2D and 3D organoid models. However, a deeper characterisation of their complex, multi-scale properties is required to optimise their translation to clinical practice. Image analysis combined with computational modelling is a powerful tool to explore mechanisms of hSC behaviour and aid clinical diagnosis and therapy. Summary: Many computational models draw on a variety of techniques, often blending continuum and discrete approaches, and have been used to describe cell differentiation and self-organisation. Machine learning tools are having a significant impact in model development and improving image classification processes for clinical diagnosis and treatment and will be the focus of much future research

Antimagic Labeling for Unions of Graphs with Many Three-Paths

Let $G$ be a graph with $m$ edges and let $f$ be a bijection from $E(G)$ to $\{1,2, \dots, m\}$. For any vertex $v$, denote by $\phi_f(v)$ the sum of $f(e)$ over all edges $e$ incident to $v$. If $\phi_f(v) \neq \phi_f(u)$ holds for any two distinct vertices $u$ and $v$, then $f$ is called an {\it antimagic labeling} of $G$. We call $G$ {\it antimagic} if such a labeling exists. Hartsfield and Ringel in 1991 conjectured that all connected graphs except $P_2$ are antimagic. Denote the disjoint union of graphs $G$ and $H$ by $G \cup H$, and the disjoint union of $t$ copies of $G$ by $tG$. For an antimagic graph $G$ (connected or disconnected), we define the parameter $\tau(G)$ to be the maximum integer such that $G \cup tP_3$ is antimagic for all $t \leq \tau(G)$. Chang, Chen, Li, and Pan showed that for all antimagic graphs $G$, $\tau(G)$ is finite [Graphs and Combinatorics 37 (2021), 1065--1182]. Further, Shang, Lin, Liaw [Util. Math. 97 (2015), 373--385] and Li [Master Thesis, National Chung Hsing University, Taiwan, 2019] found the exact value of $\tau(G)$ for special families of graphs: star forests and balanced double stars respectively. They did this by finding explicit antimagic labelings of $G\cup tP_3$ and proving a tight upper bound on $\tau(G)$ for these special families. In the present paper, we generalize their results by proving an upper bound on $\tau(G)$ for all graphs. For star forests and balanced double stars, this general bound is equivalent to the bounds given in \cite{star forest} and \cite{double star} and tight. In addition, we prove that the general bound is also tight for every other graph we have studied, including an infinite family of jellyfish graphs, cycles $C_n$ where $3 \leq n \leq 9$, and the double triangle $2C_3$

A method for improving the performance of gradient systems for diffusion-weighted MRI

The MR signal is sensitive to diffusion. This effect can be increased by the use of large, balanced bipolar gradients. The gradient systems of MR scanners are calibrated at installation and during regular servicing visits. Because the measured apparent diffusion constant (ADC) depends on the square of the amplitude of the diffusion sensitizing gradients, errors in the gradient calibration are exaggerated. If the error is varying among the different gradient axes, it will affect the estimated degree of anisotropy. To assess the gradient calibration accuracy in a whole-body MRI scanner, ADC values were calculated for a uniform water phantom along each gradient direction while monitoring the temperature. Knowledge of the temperature allows the expected diffusion constant of water to be calculated independent of the MRI measurement. It was found that the gradient axes (±x, ±y, ±z) were calibrated differently, resulting in offset ADC values. A method is presented to rescale the amplitude of each of the six principal gradient axes within the MR pulse sequence. The scaling factor is the square root of the ratio of the expected and observed diffusion constants. In addition, fiber tracking results in the human brain were noticeably affected by improving the gradient system calibration. Magn Reson Med 58:763–768, 2007. © 2007 Wiley-Liss, Inc

Impacts of climate variability and future climate change on harmful algal blooms and human health

This is the final version of the article. Available from BioMed Central via the DOI in this record.Anthropogenically-derived increases in atmospheric greenhouse gas concentrations have been implicated in recent climate change, and are projected to substantially impact the climate on a global scale in the future. For marine and freshwater systems, increasing concentrations of greenhouse gases are expected to increase surface temperatures, lower pH, and cause changes to vertical mixing, upwelling, precipitation, and evaporation patterns. The potential consequences of these changes for harmful algal blooms (HABs) have received relatively little attention and are not well understood. Given the apparent increase in HABs around the world and the potential for greater problems as a result of climate change and ocean acidification, substantial research is needed to evaluate the direct and indirect associations between HABs, climate change, ocean acidification, and human health. This research will require a multidisciplinary approach utilizing expertise in climatology, oceanography, biology, epidemiology, and other disciplines. We review the interactions between selected patterns of large-scale climate variability and climate change, oceanic conditions, and harmful algae.This work was funded in part through grants from the NSF/NIEHS Centers for Oceans and Human Health, grant numbers NSF OCE04-32479 and NIEHS P50 ES012740 (EAL), NSF OCE-0432368 and NIEHS P50 ES012736 (LEF), NIEHS P50 ES012762 and NSF OCE-0434087 (SKM, MSP). SKM, VLT and NJM also were supported in part by the West Coast Center for Oceans and Human Health (WCCOHH) as part of the NOAA Oceans and Human Health Initiative, and this is WCCOHH publication no. 26. The WCCOHH is part of the National Marine Fisheries Service's Northwest Fisheries Science Center, Seattle, Washington